Januvia was the first of the dpp-4 s to reach the public and has only been available since 2006 and the latest drug nesina, since 2013.
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Januvia and janumet should only be used during pregnancy when clearly needed.
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Patients should be instructed to promptly discontinue januvia and contact their physician if persistent severe abdominal pain occurs see warnings and precautions .
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In addition, this study included patients n 117 with more severe hyperglycemia a1c 11 or blood glucose 280 mg dl who were treated with twice daily open-label januvia 50 mg and metformin 1000 mg.
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